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TweetToSpeach

TweetToSpeach is a small Text to Speech Software. It connects to your Twitter Account and “speaks” your latest Tweets.

Socialite

Socialite is a beautiful Mac OS X application, designed to make it easy to stay in touch with the social networks and services that matter to you.

Multtiple

Multtiple is a desktop client written using Adobe AIR that supports Twitter and Tumblr.

TweetCreate

TweetCreate is an offline tool for creating, organizing, and sharing tweets.

The Archivist Desktop

The Archivist is a Windows WPF application that runs on your local system and allows you to archive tweets for later data-mining and analysis for a given search.

TweetTwain

TweetTwain is a free desktop client for Twitter to schedule tweets, manage followers, search and monitor blog feeds.

Tweetica

Tweetica is a screensaver built for OSX 10.6 (a 10.5 version is coming). It fetches real time tweets from Twitter based on hashtags set by you.

MetroTwit is a slick Twitter client for Windows. It offers a simple set of features and does a good job at it. It supports only one account. You can login via username/password or via OAuth to see your twitter stream.

Treegger

Treegger enables you to configure your IM client to work with Twitter. You can chat with online friends (bidirectional follow relationship). You don’t post a tweet, you directly send message to you friend without publishing it somewhere. Treegger does not store any data, credentials or messages, all contents just transit between you and our servers [...]

Tweativity

Tweativity is a free desktop application for Windows that integrates with Twitter and gives you access to high quality background images that you can apply to your Twitter profile in a seamless experience.

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