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TextOnly Twitter is a simple Chrome extension which would display tweeted links/articles in textonly mode on Google Chrome.
Bonfire.im changes the Twitter experience in quite a fundamental way by adding IM-syle presence.
Tribalfish is a free browser extension for Chrome, Firefox and Safari that lets Twitter users turn tweets into interactive, persistent discussions with multiple people in private and public groups.
Scribbr is an application that allows you to create ‘freehand’ drawings that you can post to Twitter along with a description. It uses OAuth to login so you don’t need to provide your Twitter password to the app. Scribbr works on Firefox, Safari and Chrome.