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JustUpdate is an open-source application for your iPhone/iPod that allows you to send status updates to Twitter. As described by its authors, So all you want in a web app is an update field, and perhaps a counter of remaining characters, one that if the update fails won’t lose your text.
Tremors is a bit of fun. It tries to show Twitter activity from specific places, and how people feel about that place. Built in just a few days, it currently monitors tweets from London, New York, Austin and San Francisco.
The Anonymous group has released a Twitter app titled URGE to enable you to tweet faster on topics that interest you.
SickCity aims to do a realtime disease detection for your city from messages on Twitter (and soon Facebook). It does this by looking for tweets related to flu, food poisoning, headcolds, chicken pox & sore throats over a one month period.
TweetToSpeach is a small Text to Speech Software. It connects to your Twitter Account and “speaks” your latest Tweets.
The Archivist is a Windows WPF application that runs on your local system and allows you to archive tweets for later data-mining and analysis for a given search.
Chromed Bird is an open source Chromium extension that allows you to follow your Twitter account using Google Chrome.
Gotweet is a simple command-line Twitter client in Go programming language. Gotweet is open-source.